LOCALITE

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    Localite Neuro Navigation

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  • Slide Title

    Localite Neuro Navigation

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Localite TMS Navigator

The LOCALITE TMS Navigator is an image-based navigation system for targeting transcranial magnetic stimulation.
In neuroscience transcranial magnetic stimulation (TMS) of the human brain has established itself as a means to examine processes in the central nervous system. The noninvasive technology is based on strong magnetic fields which can stimulate as well as inhibit some parts of the brain. Specific areas of the brain assumed to be involved in particular processes are treated by TMS, therefore a precisely targeted stimulation is crucial for valid results.

Localite provide solutions for Classic TMS, an MRI Compatible edition and a Robotic edition.


Targeted Stimulation of Brain Areas
The area of the brain assumed to be involved in the process being investigated is subjected to magnetic pulses. They are produced by TMS coils, fed by pulse generators, that allow the researcher to control the strength, shape, duration and frequency of the magnetic pulse. So far, TMS coils have been positioned based on the researcher's knowledge of general brain anatomy and additional hypotheses under investigation. Information about the individual subject, e.g. gained from functional imaging, can be used only indirectly. While the stimulation of motor-related brain areas may provide immediate feedback to the neuroscientist, the effect of stimulating areas involved in higher-order cognitive functions cannot be measured directly.
 
Navigation-Assisted Stimulation
Research as well as diagnostic or therapeutic applications of TMS need precise information about the brain area stimulated, and on the direction and shape of the magnetic pulse. The LOCALITE TMS Navigator helps to position the coil very precisely in reference to the subjects brain shown in an individual anatomical MR dataset.
In the following three aspects TMS usage is assistet by the various functions of the TMS Navigator:
  • Target definition und target guidance
  • Reproducebility
  • Control and documentation
Configurable Components
It is possible to configure hard- and software components individually. As result you will receive a system that is tailored to your specific demand and suits to your budget.

Functional Data

Allows to import functional MRI or nuclear medicine images. Supported data formats are: DICOM,NIfTI, Analyze and Interfile. To map functional data onto anatomical data Localite TMS Navigator features intuitive step-by-step registration procedures. As soon as images are coregistrated functional information can be overlayed and the visualization can be adjusted in color and opacity. Thus, preinterventional functional data can be incorporated to improve planning of stimulation.

EEG
Step by step you are guided through the acquisition of electrode positions. You can select the applicable EEG system from a list of predefined patterns — or simply create one by yourself. Even without anatomical data you are able to export the patterns into different coordinate systems (DICOM, MNI, Talaraich).

MagVenture Stimulator Connection Package
The connection package links your MagVenture Stimulator with your TMS Navigator. From now on information like temperature or amplitude will be displayed directly in the software interface. But there is more: Communication is also possible the other way round — important parameters can be transmitted to the stimulator. This simplifies the process, because information you would enter manually can now exchanged automatically.

Stimulation Response Export
Stimulation Response Export lets you export stimulation data (location, amplitude) along with the acquired stimulation responses (e.g. MEP) as functional image data. Thus you are able to create a comprehensive documentation of stimulation and its effects. The resulting image data can be imported into a navigation system again any time later.
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